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TXA2 (短名 ),
产品名称:

General TXA2/ Thromboxane A2 CLIA Kit
血栓素A2

货号:

U1396Ge

商标:
EIAab®
监管等级:
检测方法:
CLIA
实验类型:
Competitive
检测范围:
0.39-25pg/mL
特异性:
Natural and recombinant general Thromboxane A2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
General TXA2 CLIA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


Sub Unit:
N/A


Function:
Thromboxane A2 (TXA2) is a thromboxane. It is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. This is achieved by mediating expression of the glycoprotein complex GP IIb/IIIa in the cell membrane of platelets. Circulating fibrinogen binds these receptors on adjacent platelets, further strengthening the clot.


Location:
TXA2 is generated from prostaglandin H2 by thromboxane-A synthase. Aspirin irreversibly inhibits platelet cyclooxygenase 1 preventing the formation of prostaglandin H2, and therefore thromboxane A2.


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