General TXA2/ Thromboxane A2 CLIA Kit
血栓素A2

货号:

U1396Ge

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

实验类型:

Competitive

检测范围:

0.39-25pg/mL

特异性:

Natural and recombinant general Thromboxane A2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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General TXA2 CLIA Kit

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通用注释

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N/A

功能:

Thromboxane A2 (TXA2) is a thromboxane. It is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. This is achieved by mediating expression of the glycoprotein complex GP IIb/IIIa in the cell membrane of platelets. Circulating fibrinogen binds these receptors on adjacent platelets, further strengthening the clot.

Location:

TXA2 is generated from prostaglandin H2 by thromboxane-A synthase. Aspirin irreversibly inhibits platelet cyclooxygenase 1 preventing the formation of prostaglandin H2, and therefore thromboxane A2.