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CS (短名 ),
产品名称:

General CS/ Chondroitin sulfate CLIA Kit
硫酸软骨素

货号:

U0723Ge

商标:
EIAab®
监管等级:
检测方法:
CLIA
特异性:
Natural and recombinant general Chondroitin sulfate
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
General CS CLIA Kit
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产品说明书


通用注释


Sub Unit:
N/A


Function:
Chondroitin sulfate readily interacts with proteins in the extracellular matrix due to its negative charges. These interactions are important for regulating a diverse array of cellular activities. The lecticans are a major part of the brain extracellular matrix, where the chondroitin sugar chains function to stabilize normal brain synapses as part of perineuronal nets. The levels of chondroitin sulfate proteoglycans are vastly increased after injury to the central nervous system where they act to prevent regeneration of damaged nerve endings. Although these functions are not as well characterized as those of heparan sulfate, new roles continue to be discovered for the chondroitin sulfate proteoglycans.


Location:
Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan. A chondroitin chain can have over 100 individual sugars, each of which can be sulfated in variable positions and quantities. Chondroitin sulfate is an important structural component of cartilage and provides much of its resistance to compression. Along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis.


该产品尚未在任何出版物中被引用。

[1].
"Single nucleotide polymorphisms in succinate dehydrogenase subunits and citrate synthase genes: association results for impaired spermatogenesis."

[2].
"[Cloning and tissue expression pattern analysis of the human citrate synthase cDNA]."

[3].
"Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase."

[4].
"Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation."

[5].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[6].
"Identification and characterization of the mitochondrial targeting sequence and mechanism in human citrate synthase."

[7].
"Interactive domains for chaperone activity in the small heat shock protein, human alphaB crystallin."

[8].
"Enhanced citrate synthase activity in human pancreatic cancer."

[9].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[10].
"Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
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