HYP (短名 ),
通用注释
亚单元:
N/A
功能:
Hydroxyproline is a major component of the protein collagen. Hydroxyproline and proline play key roles for collagen stability. They permit the sharp twisting of the collagen helix. Hydroxyproline is found in few proteins other than collagen. For this reason, hydroxyproline content has been used as an indicator to determine collagen and/or gelatin amount.
Location:
Hydroxyproline is produced by hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase following protein synthesis (as a post-translational modification). The enzyme catalysed reaction takes place in the lumen of the endoplasmic reticulum. Although it is not directly incorporated into proteins, hydroxyproline comprises roughly 4% of all amino acids found in animal tissue, more than seven amino acids which are directly incorporated.
验证序列:
[1].
Eun-Jung Park ,Jinkyu Roh ,Soo-Nam Kim ,Min-sung Kang ,Young-Ah Han ,Younghun Kim ,Jin Tae Hong ,Kyunghee Choi
From:
Arch Toxicol
[2].
Christoph Schmaderer,., Chang Jiang Xing , Gaby Anderson , Rob Hermans, Jens Lutz , Uwe Heemann , Marcus Baumann
From:
Life Sciences
[4].
SH Lee, EJ Lee, SY Lee, et al.
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