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VTN (基因名), Vitronectin (蛋白名), vtnc_human.
产品名称:

Human VTN/ Vitronectin Recombinant Protein
玻连蛋白

货号:

R1041h

商标:
EIAab®
监管等级:
别名:

S-protein, Serum-spreading factor, V75, VN

序列号:
P04004
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human VTN Protein
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Human VTN Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 17q11.2 by HGNC 17q11.2 by Entrez Gene 17q11.2 by Ensembl
VTN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Exists in two forms: a single chain 75 kDa form (V75) and a clipped form composed of two chains (65 kDa and 10 kDa) (V65+V10) which are held together by a disulfide bond. Interacts with SERPINE1/PAI1, insulin and C1QBP.


功能:
Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.


亚细胞位置:
Secreted Extracellular space



[1].
"Phosphorylation of vitronectin by casein kinase II. Identification of the sites and their promotion of cell adhesion and spreading."

[2].
"The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor."

[3].
"Identification of a PAI-1 binding site in vitronectin."

[4].
"Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin."

[5].
"The phosphorylation of the two-chain form of vitronectin by protein kinase A is heparin dependent."

[6].
"Nucleotide sequence and organization of the human S-protein gene: repeating peptide motifs in the "pexin" family and a model for their evolution."

[7].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[8].
"Neisseria meningitidis Opc invasin binds to the sulphated tyrosines of activated vitronectin to attach to and invade human brain endothelial cells."

[9].
"The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors."

[10].
"Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells."
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