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Hras (基因名), GTPase HRas (蛋白名), rash_mouse.
产品名称:

Mouse Hras/ GTPase HRas Recombinant Protein
GTP酶HRas

货号:

R1294m

商标:
EIAab®
监管等级:
别名:

H-Ras-1, Transforming protein p21, c-H-ras, p21ras, Hras1

序列号:
Q61411
来源:
E.coli
种属:
Mouse
标签:
His
序列:
Internal
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Mouse Hras Protein
规格 & 价格: cart
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Mouse Hras Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Forms a signaling complex with RASGRP1 and DGKZ (By similarity). In its GTP-bound form interacts with PLCE1 (By similarity). Interacts with TBC1D10C and RASSF5 (By similarity). Interacts with PDE6D (By similarity). Interacts with IKZF3 (By similarity). Found in a complex with at least BRAF, HRAS, MAP2K1, MAPK3 and RGS14 (By similarity). Interacts (active GTP-bound form) with RGS14 (via RBD 1 domain) (By similarity). Interacts with RACK1 (By similarity). Interacts with RAPGEF2 (By similarity). Interacts with RGL3 (PubMed:10869344). Interacts with HSPD1 (PubMed:1347942). Interacts with PIK3CG; the interaction is required for membrane recruitment and beta-gamma G protein dimer-dependent activation of the PI3K gamma complex PIK3CG:PIK3R6 (PubMed:19906996). Interacts (in GTP-bound form) with Oog1 (PubMed:16580637).


功能:
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.


亚细胞位置:
Cell membrane Cell membrane Lipid-anchor Cytoplasmic side Golgi apparatus Golgi apparatus membrane Lipid-anchor Shuttles between the plasma membrane and the Golgi apparatus. The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form (By similarity).


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