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Mc4r (基因名), Melanocortin receptor 4 (蛋白名), mc4r_rat.
产品名称:

Rat Mc4r/ Melanocortin receptor 4 Recombinant Protein
黑皮质素受体4

货号:

R11964r

商标:
EIAab®
监管等级:
别名:

MC4-R

序列号:
P70596
来源:
E.coli
种属:
Rat
标签:
His
序列:
1-113aa
预估分子量:
12.43 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Rat Mc4r Protein
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Rat Mc4r Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Rat Mc4r Protein
Recombinant rat Mc4r protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Interacts with ATRNL1 (By similarity). Homodimer; disulfide-linked, also forms higher order oligomers. Interacts with MGRN1, but does not undergo MGRN1-mediated ubiquitination; this interaction competes with GNAS-binding and thus inhibits agonist-induced cAMP production. Interacts with MRAP and MRAP2; these associated factors increase ligand-sensitivity and generation of cAMP.


功能:
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).


亚细胞位置:
Cell membrane Multi-pass membrane protein


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