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首页  >  重组蛋白  >  Human INS Recombinant Protein
INS (基因名), Insulin (蛋白名), ins_human.
产品名称:

Human INS/ Insulin Recombinant Protein
胰岛素

货号:

R0448h

商标:
EIAab®
监管等级:
序列号:
P01308
来源:
E.coli
种属:
Human
标签:
His
序列:
25-110aa
预估分子量:
9.46 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human INS Protein
规格 & 价格: cart
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Human INS Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 11p15.5 by HGNC 11p15.5 by Entrez Gene 11p15.5 by Ensembl
INS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Heterodimer of a B chain and an A chain linked by two disulfide bonds (PubMed:25423173).


功能:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.


亚细胞位置:
Secreted



[1].
"Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood."

[2].
"Insulin gene mutations as a cause of permanent neonatal diabetes."

[3].
"Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR."

[4].
"A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia."

[5].
"Sequence of the human insulin gene."
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