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ACE (基因名), Angiotensin-converting enzyme (蛋白名), ace_human.
产品名称:

Human ACE/ Angiotensin-converting enzyme Recombinant Protein
血管紧张素转化

货号:

R0004h

商标:
EIAab®
监管等级:
别名:

Dipeptidyl carboxypeptidase I, Kininase II, CD143, ACE, DCP, DCP1

序列号:
P12821
来源:
E.coli
种属:
Human
标签:
His
序列:
216-416aa
预估分子量:
22.11 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ACE Protein
规格 & 价格: cart
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Human ACE Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ACE Protein
Recombinant human ACE protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 17q23.3 by HGNC 17q23.3 by Entrez Gene 17q23.3 by Ensembl
ACE Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Cytoplasm Detected in both cell membrane and cytoplasm in neurons.



[1].
"Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme."

[2].
"Polymorphisms in NOS3, ACE and PAI-1 genes and risk of spontaneous recurrent miscarriage in the Gaza Strip."

[3].
"Endothelial nitric oxide synthase, angiotensin-converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy."

[4].
"Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study."

[5].
"Genetic risk factors for arterial ischemic stroke in children: a possible MTHFR and eNOS gene-gene interplay?"

[6].
"Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme."

[7].
"Polymorphisms in NOS3, ACE and PAI-1 genes and risk of spontaneous recurrent miscarriage in the Gaza Strip."

[8].
"Endothelial nitric oxide synthase, angiotensin-converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy."

[9].
"Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study."

[10].
"Genetic risk factors for arterial ischemic stroke in children: a possible MTHFR and eNOS gene-gene interplay?"
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