Sipa1l1 (基因名), Signal-induced proliferation-associated 1-like protein 1 (蛋白名), si1l1_rat.
产品名称:
Rat Sipa1l1/ Signal-induced proliferation-associated 1-like protein 1 CLIA Kit
信号诱导增殖相关蛋白1样蛋白1
货号:
U6550r
商标:
EIAab®
监管等级:
别名:
SPA-1-like protein p1294, Spine-associated Rap GTPase-activating protein, SPAR, SIPA1-like protein 1, Spa1
检测方法:
CLIA
特异性:
Natural and recombinant rat Signal-induced proliferation-associated 1-like protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts (via PDZ domain) with EPHA4 (via PDZ motif); controls neuronal morphology through regulation of the RAP1 (RAP1A or RAP1B) and RAP2 (RAP2A, RAP2B or RAP2C) GTPases (By similarity). Interacts with DLG4, PDLIM5, PDLIM7 and LZTS3. Interacts with the actin cytoskeleton.
功能:
Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis.
亚细胞位置:
Cytoplasm
Cytoskeleton
Cell junction
Synapse
Postsynaptic cell membrane
Postsynaptic density
Cell junction
Synapse
Synaptosome
Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons.
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验证序列:
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