Human IL23A/ Interleukin-23 subunit alpha CLIA Kit
白介素23α亚基

货号:

U0384h

商标:

EIAab^®

监管等级:

RUO

别名:

Interleukin-23 subunit p19, IL-23p19, UNQ2498/PRO5798, IL-23 subunit alpha, SGRF

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant human Interleukin-23 subunit alpha

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Human IL23A CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

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通用注释

亚单元:

Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-23.

功能:

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

亚细胞位置:

Secreted Secreted upon association with IL12B.

数据库链接

UniGene:

Hs.382212

SMR:

Q9NPF7

STRING:

9606.ENSP00000228534

KEGG:

hsa:51561

MIM: