C4BPA (基因名), C4b-binding protein alpha chain (蛋白名), c4bpa_human.
产品名称:
Human C4BPA/ C4b-binding protein alpha chain CLIA Kit
C4b结合蛋白α链
货号:
U0761h
商标:
EIAab®
监管等级:
别名:
Proline-rich protein, PRP, C4bp, C4BP
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
0.195-12.5ng/mL
特异性:
Natural and recombinant human C4b-binding protein alpha chain
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Immunology
通用注释
亚单元:
Disulfide-linked complex of alpha and beta chains of 3 possible sorts: a 570 kDa complex of 7 alpha chains and 1 beta chain, a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. The central body of the alpha chain homopolymer supports tentacles, each with the binding site for C4b at the end.
功能:
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
亚细胞位置:
Secreted
[1].
J Ma, X Luo, Q Wu, et al.
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