首页 > 重组蛋白 > Human AIF1 Recombinant Protein

AIF1 (基因名), Allograft inflammatory factor 1 (蛋白名), aif1_human.

产品名称:

Human AIF1/ Allograft inflammatory factor 1 Recombinant Protein
同种异体移植炎症因子1

货号:

R1251h

商标:

EIAab^®

监管等级:

RUO

别名:

Ionized calcium-binding adapter molecule 1, Protein G1, AIF-1, G1, IBA1

序列号:

P55008

来源:

E.coli

种属:

Human

标签:

His

序列:

2-147aa

预估分子量:

16.06 kDa (monomer)

纯度:

Greater than 95% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Cancer

规格 & 价格:

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Human AIF1 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

The PCR product of human AIF1 gene was determined by 1% Agarose stained with EB.

Recombinant human AIF1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 6p21.33 by HGNC 6p21.33 by Entrez Gene 6p21.33 by Ensembl

AIF1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Homodimer (Potential). Monomer. Interacts with LCP1.

功能:

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

亚细胞位置:

Cytoplasm Cytoskeleton Cell projection Ruffle membrane Peripheral membrane protein Cytoplasmic side Cell projection Phagocytic cup Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.

数据库链接

UniGene:

Hs.76364

SMR:

P55008

STRING:

9606.ENSP00000365227

KEGG:

hsa:199

MIM:

601833

Uniprot:

P55008

相关产品

Mouse Aif1 ELISA Kit

Rat Aif1 ELISA Kit

Bovine AIF1 ELISA Kit

Pig AIF1 ELISA Kit

Mouse Aif1 CLIA Kit

序列长度:

147

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

147:

FSYPDFLRMM | LGKRSAILKM | ILMYEEKARE | KEKPTGPPAK | KAISELP

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries."

(PMID: 8912632)

[2].

"Structural and functional characterization of human Iba proteins."

(PMID: 18699778)

[3].

"Association of allograft inflammatory factor-1 gene polymorphism with rheumatoid arthritis."

(PMID: 18721278)

[4].

"Allograft inflammatory factor-1 and tumor necrosis factor single nucleotide polymorphisms in systemic sclerosis."

(PMID: 17498268)

[5].

"An allograft inflammatory factor 1 (AIF1) single nucleotide polymorphism (SNP) is associated with anticentromere antibody positive systemic sclerosis."

(PMID: 17522098)

[6].

"X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding."

(PMID: 17011575)

[7].

"Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies."

(PMID: 16049345)

[8].

"AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF."

(PMID: 15117732)

[9].

"TNF, TNF receptor type 1, and allograft inflammatory factor-1 gene polymorphisms in Japanese patients with type 1 diabetes."

(PMID: 12559634)

[10].

"A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC."

(PMID: 10202016)

[1].

人同种异体移植炎症因子1(AIF1)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人同种异体移植炎症因子1(AIF1)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人同种异体移植炎症因子1(AIF1)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人同种异体移植炎症因子1(AIF1)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人同种异体移植炎症因子1(AIF1)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人同种异体移植炎症因子1(AIF1)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人同种异体移植炎症因子1(AIF1)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人同种异体移植炎症因子1(AIF1)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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