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HAT1 (基因名), Histone acetyltransferase type B catalytic subunit (蛋白名), hat1_human.
产品名称:

Human HAT1/ Histone acetyltransferase type B catalytic subunit ELISA Kit
组蛋白乙酰转移酶B型催化亚单位

货号:

E15268h

商标:
EIAab®
监管等级:
别名:

Histone acetyltransferase 1, KAT1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.078ng/mL
特异性:
Natural and recombinant human Histone acetyltransferase type B catalytic subunit
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Development Biology
Human HAT1 ELISA Kit
规格 & 价格: cart
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Human HAT1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A. The interaction is dependent of the ability of RBBP7 to bind to the N-terminus of histones. Component of the histone H3.1 and H3.3 complexes.


功能:
Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.


亚细胞位置:
Isoform B Cytoplasm Nucleus Nucleus matrix Nucleus Nucleoplasm Localization is predominantly nuclear in normal cells. Treatment with hydrogen peroxide or ionizing radiation enhances nuclear localization through redistribution of existing protein.


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