首页 > 重组蛋白 > Human ATAD3B Recombinant Protein

ATAD3B (基因名), ATPase family AAA domain-containing protein 3B (蛋白名), atd3b_human.

产品名称:

Human ATAD3B/ ATPase family AAA domain-containing protein 3B Recombinant Protein
atp酶家族AAA结构域蛋白3B

货号:

R4358h

商标:

EIAab^®

监管等级:

RUO

别名:

AAA-TOB3, KIAA1273, TOB3

序列号:

Q5T9A4

来源:

E.coli

种属:

Human

标签:

His

序列:

2-246aa

预估分子量:

26.95 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human ATAD3B Protein

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产品说明书

数据表:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

The PCR product of human ATAD3B gene was determined by 1% Agarose stained with EB.

Recombinant human ATAD3B protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 1p36.33 by HGNC 1p36.33 by Entrez Gene 1p36.33 by Ensembl

ATAD3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Forms heterooligomers with ATAD3A. Interacts with components of the mitochondrial ribosome, including MRPL11 and MRPS18B, and with other proteins involved in mitochondrial RNA metabolism, possibly via interaction with ATAD3A. Interacts with GADD45GIP1.

功能:

May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes.

亚细胞位置:

Mitochondrion inner membrane Peripheral membrane protein Has been found to co-purify with nucleoids (PubMed:22453275). Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A.

数据库链接

UniGene:

Hs.729021

STRING:

9606.ENSP00000311766

KEGG:

hsa:83858

MIM:

612317

Pfam:

PF00004

Uniprot:

Q5T9A4

相关产品

Human ATAD3B ELISA Kit

Human ATAD3B CLIA Kit

Human ATAD3B Polyclonal Antibody

Human ATAD3B Monoclonal Antibody

Human ATAD3B

序列长度:

648

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

648:

DPSYPCLAGP | CTFRICSWMG | TGLCPGPLSP | RMSCGGGRPF | CPPGHPLL

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

(PMID: 10574462)

[2].

"ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A."

(PMID: 22664726)

[3].

"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

(PMID: 20877624)

[4].

"The DNA sequence and biological annotation of human chromosome 1."

(PMID: 16710414)

[5].

"Molecular characterization of the tumor-associated antigen AAA-TOB3."

(PMID: 16909202)

[6].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."

(PMID: 14702039)

[7].

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

(PMID: 15489334)

[8].

"Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics."

(PMID: 28330616)

[9].

"Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation."

(PMID: 28416769)

[10].

"ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism."

(PMID: 28549128)

[1].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人atp酶家族AAA结构域蛋白3B(ATAD3B)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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