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Traf3ip1 (基因名), TRAF3-interacting protein 1 (蛋白名), MIPT3_RAT.
产品名称:

Rat Traf3ip1/ TRAF3-interacting protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Intraflagellar transport protein 54 homolog, Microtubule-interacting protein associated with TRAF3, MIP-T3, Ift54, Mipt3

序列号:
Q5XIN3
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Rat Traf3ip1 Protein
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Rat Traf3ip1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Component of the IFT complex B, at least composed of IFT20, IFT22, HSPB11/IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80, IFT81, and IFT88. Interacts with IFT88 (By similarity). Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1 (By similarity). Interacts with MAP4.


功能:
Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity). Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis.


亚细胞位置:
Cytoplasm Cytoskeleton Cell projection Cilium Cytoplasm Cytoskeleton Cilium axoneme Cytoplasm Cytoskeleton Cilium basal body Microtubules. In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip.


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