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MFAP5 (基因名), Microfibrillar-associated protein 5 (蛋白名), MFAP5_HUMAN.
产品名称:

Human MFAP5/ Microfibrillar-associated protein 5 Recombinant Protein
微原纤维结合蛋白5

货号:

R11955h

商标:
EIAab®
监管等级:
别名:

MP25, Microfibril-associated glycoprotein 2, MAGP-2, MFAP-5, MAGP2

序列号:
Q13361
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MFAP5 Protein
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Human MFAP5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12p13.31 by HGNC 12p13.31 by Entrez Gene 12p13.31 by Ensembl
MFAP5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with TGFB2. Interacts with BMP2. Interacts with FBN1 (via N-terminal domain) and FBN2.


功能:
May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils (PubMed:8557636).


亚细胞位置:
Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"The exon structure of the human MAGP-2 gene. Similarity with the MAGP-1 gene is confined to two exons encoding a cysteine-rich region."

[2].
"Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25)"

[3].
"MFAP5 loss-of-function mutations underscore the involvement of matrix alteration in the pathogenesis of familial thoracic aortic aneurysms and dissections."

[4].
"A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2."

[5].
"Microfibril-associate glycoprotein-2 (MAGP-2) promotes angiogenic cell sprouting by blocking notch signaling in endothelial cells."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer."

[8].
"MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer."

[9].
"Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics."

[10].
"MAGP2 controls Notch via interactions with RGD binding integrins: Identification of a novel ECM-integrin-Notch signaling axis."
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