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首页  >  重组蛋白  >  Human MC2R Recombinant Protein
MC2R (基因名), Adrenocorticotropic hormone receptor (蛋白名), ACTHR_HUMAN.
产品名称:

Human MC2R/ Adrenocorticotropic hormone receptor Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R, ACTH receptor, ACTHR

序列号:
Q01718
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human MC2R Protein
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Human MC2R Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 18p11.2 by HGNC 18p11.2 by Entrez Gene 18p11.2 by Ensembl
MC2R Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).


功能:
Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Isolated Addison's disease is unlikely to be caused by mutations in MC2R, MRAP or STAR, three genes responsible for familial glucocorticoid deficiency."

[2].
"Phenotypic characteristics of familial glucocorticoid deficiency (FGD) type 1 and 2."

[3].
"Genetic polymorphisms of MC2R gene associated with responsiveness to adrenocorticotropic hormone therapy in infantile spasms."

[4].
"Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction."

[5].
"ACTH receptor promoter polymorphism associates with severity of premature adrenarche and modulates hypothalamo-pituitary-adrenal axis in children."

[6].
"Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2."

[7].
"Characterization of an adrenocorticotropin (ACTH) receptor promoter polymorphism leading to decreased adrenal responsiveness to ACTH."

[8].
"Clinical, genetic, and functional characterization of adrenocorticotropin receptor mutations using a novel receptor assay."

[9].
"Hereditary isolated glucocorticoid deficiency is associated with abnormalities of the adrenocorticotropin receptor gene."

[10].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."
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