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首页  >  重组蛋白  >  Human APOBEC1 Recombinant Protein
APOBEC1 (基因名), C->U-editing enzyme APOBEC-1 (蛋白名), ABEC1_HUMAN.
产品名称:

Human APOBEC1/ C->U-editing enzyme APOBEC-1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Apolipoprotein B mRNA-editing enzyme 1, HEPR, mRNA(cytosine(6666)) deaminase 1

序列号:
P41238
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human APOBEC1 Protein
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Human APOBEC1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 12p13.31 by HGNC 12p13.31 by Entrez Gene 12p13.31 by Ensembl
APOBEC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP.


功能:
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease."

[2].
"C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme."

[3].
"Human apolipoprotein B RNA editing deaminase gene (APOBEC1)."

[4].
"Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein."

[5].
"Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor."

[6].
"The expression of apoB mRNA editing factors is not the sole determinant for the induction of editing in differentiating Caco-2 cells."

[7].
"Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus."

[8].
"Hypermutation induced by APOBEC-1 overexpression can be eliminated."

[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[10].
"Simultaneous expression of apolipoprotein B mRNA editing enzyme and scavenger receptor BI mediated by a therapeutic gene expression system."
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