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首页  >  重组蛋白  >  Mouse Prkab2 Recombinant Protein
Prkab2 (基因名), 5'-AMP-activated protein kinase subunit beta-2 (蛋白名), AAKB2_MOUSE.
产品名称:

Mouse Prkab2/ 5'-AMP-activated protein kinase subunit beta-2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

AMPK subunit beta-2

序列号:
Q6PAM0
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Mouse Prkab2 Protein
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Mouse Prkab2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3).


功能:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).


亚细胞位置:
N/A


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