首页 > 一抗 > S100B Antibody

S100B (基因名), Protein S100-B (蛋白名), s100b_human.

产品名称:

S100B Antibody

货号:

P0567Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B

序列号:

P04271

反应性:

human

免疫原:

Recombinant human S100B Protein (R0567h)

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cancer

规格 & 价格:

关注

Human S100B Polyclonal Antibody

邮箱 *

消息 *

Please 登录.

产品说明书

数据表:

MSDS:

在线询价

数据
文献 ( 1 )
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

S100B antibody detects S100B protein at glial cell on mouse hind brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse hind brain. S100B antibody dilution: 1:200.

通用注释

亚单元:

Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. The S100B dimer binds two molecules of STK38. Interacts with CACYBP in a calcium-dependent manner. Interacts with ATAD3A; this interaction probably occurs in the cytosol prior to ATAD3A mitochondrial targeting. Interacts with S100A6. The S100B dimer interacts with two molecules of CAPZA1. Interacts with AGER. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.

功能:

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

亚细胞位置:

Cytoplasm Nucleus

数据库链接

UniGene:

Hs.422181

SMR:

P04271

STRING:

9606.ENSP00000291700

KEGG:

hsa:6285

MIM: