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MGME1 (基因名), Mitochondrial genome maintenance exonuclease 1 (蛋白名), mgme1_human.
产品名称:

MGME1 Antibody

货号:

P15155Rb

商标:
EIAab®
监管等级:
别名:

C20orf72, DDK1

序列号:
Q9BQP7
反应性:
human, mouse
免疫原:
Synthetic peptide
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
  • Human MGME1 Polyclonal Antibody
  • Human MGME1 Polyclonal Antibody
  • Human MGME1 Polyclonal Antibody
规格 & 价格: cart
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Human MGME1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human MGME1 Polyclonal Antibody
Immunohistochemical staining of human colon with MGME1 polyclonal antibody shows strong cytoplasmic positivity in glandular cells at 1:50 dilution.
通用注释


亚单元:
N/A


功能:
Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.


亚细胞位置:
Mitochondrion


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