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METRNL (基因名), Meteorin-like protein (蛋白名), metrl_human.

产品名称:

METRNL Antibody

货号:

P7391Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Subfatin

序列号:

Q641Q3

反应性:

human

免疫原:

corresponding to a sequence mapping at the 46-311aa of Q641Q3

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cell Biology

规格 & 价格:

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Human METRNL Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

2293T cells lysate was subjected to SDS-PAGE followed by Western Blot with METRNL antibody at dilution of 1:400

Immunohistochemistry of paraffin-embedded human kidney tissue using METRNL antibody at 1:100 dilution.

通用注释

亚单元:

N/A

功能:

Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.378821

STRING:

9606.ENSP00000315731

KEGG:

hsa:284207

MIM:

616241

Uniprot: