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ARNT (基因名), Aryl hydrocarbon receptor nuclear translocator (蛋白名), arnt_human.
产品名称:

ARNT Antibody

货号:

P2286Rb-h

商标:
EIAab®
监管等级:
别名:

Class E basic helix-loop-helix protein 2, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, bHLHe2, HIF-1-beta, ARNT protein, BHLHE2

序列号:
P27540
反应性:
human
免疫原:
Synthetic peptide
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Epigenetics
  • Human ARNT Polyclonal Antibody
  • Human ARNT Polyclonal Antibody
  • Human ARNT Polyclonal Antibody
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Human ARNT Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ARNT Polyclonal Antibody
Western Blot analysis of ARNT expression in transfected 293T cell line by ARNT monoclonal antibody
Anti-ARNT antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
通用注释


亚单元:
Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with TACC3 (By similarity). Interacts with NOCA7. Heterodimer with HIF1A.


功能:
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.


亚细胞位置:
Nucleus


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