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AHI1 (基因名), Jouberin (蛋白名), ahi1_human.
产品名称:

Human AHI1/ Jouberin ELISA Kit
Jouberin

货号:

E2445h

商标:
EIAab®
监管等级:
别名:

Abelson helper integration site 1 protein homolog, AHI-1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.052ng/mL
特异性:
Natural and recombinant human Jouberin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human AHI1 ELISA Kit
规格 & 价格: cart
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Human AHI1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Self-associates (PubMed:23532844). Part of the tectonic-like complex (also named B9 complex). Interacts with MKS1. Interacts with NPHP1; probably as heterodimers and/or AHI1(2):NPHP1(2) heterotetramers. Interacts (via SH3 domain) with the dynamin GTPase DNM2. Interacts with HAP1; probably as AHI1(2):HAP1(2) heterotetramers. Interacts with RAB8A (By similarity). Interacts with CEND1.


功能:
Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation.


亚细胞位置:
Cytoplasm Cytoskeleton Cilium basal body Cell junction Adherens junction Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriole


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