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Adam17 (基因名), Disintegrin and metalloproteinase domain-containing protein 17 (蛋白名), ada17_rat.
产品名称:

Rat Adam17/ Disintegrin and metalloproteinase domain-containing protein 17 ELISA Kit
解整合素和金属蛋白酶结构域蛋白17

货号:

E1319r

商标:
EIAab®
监管等级:
别名:

TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM 17, Tace

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
39.8pg/mL
特异性:
Natural and recombinant rat Disintegrin and metalloproteinase domain-containing protein 17
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Rat Adam17 ELISA Kit
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with MAD2L1, MAPK14 and MUC1.


功能:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。
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