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Mprip (基因名), Myosin phosphatase Rho-interacting protein (蛋白名), MPRIP_MOUSE.
产品名称:

Mouse Mprip/ Myosin phosphatase Rho-interacting protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Rho-interacting protein 3, p116Rip, RIP3, Kiaa0864, Mrip, Rhoip3

检测方法:
ELISA
特异性:
Natural and recombinant mouse Myosin phosphatase Rho-interacting protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Mprip ELISA Kit
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Mouse Mprip ELISA Kit
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通用注释


亚单元:
Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains. Interacts with MYZAP. Binds F-actin through its N-terminus.


功能:
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.


亚细胞位置:
Cytoplasm Cytoskeleton Colocalizes with F-actin.


该产品尚未在任何出版物中被引用。
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