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Mink1 (基因名), Misshapen-like kinase 1 (蛋白名), MINK1_RAT.
产品名称:

Rat Mink1/ Misshapen-like kinase 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

GCK family kinase MiNK, MAPK/ERK kinase kinase kinase 6, Misshapen/NIK-related kinase, Mitogen-activated protein kinase kinase kinase kinase 6, MEK kinase kinase 6, Map4k6, Mink

检测方法:
ELISA
特异性:
Natural and recombinant rat Misshapen-like kinase 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Mink1 ELISA Kit
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Rat Mink1 ELISA Kit
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通用注释


亚单元:
Interacts with RAP2A and NCK1 (By similarity). Interacts with TANC1.


功能:
Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.


亚细胞位置:
Cytoplasm Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell projection Axon Cell projection Dendrite


该产品尚未在任何出版物中被引用。
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