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Mgat4d (GeneName), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (ProteinName), MGT4D_MOUSE.
Product Name:

Mouse Mgat4d/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

N-acetylglucosaminyltransferase MGAT1 inhibitory protein, GlcNAcT-I inhibitory protein

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Mgat4d ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Isoform 2 self-associates; specifically in the endoplasmic reticulum prior to its translocation to the Golgi. Isoform 1 and isoform 2 interact with MGAT1, MGAT3 and MAN2A2; isoform 2 interacts specifically with MGAT1 in the Golgi.


Function:
Isoform 2: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.


Subcellular Location:
Isoform 1 Golgi apparatus membrane Single-pass type II membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain."

[2].
"A testis-specific regulator of complex and hybrid N-glycan synthesis."

[3].
"ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis."

[4].
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."

[5].
"Genome-wide association with select biomarker traits in the Framingham Heart Study."

[6].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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