Mgat4d (GeneName), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (ProteinName), MGT4D_MOUSE.
Mouse Mgat4d/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D ELISA Kit
N-acetylglucosaminyltransferase MGAT1 inhibitory protein, GlcNAcT-I inhibitory protein
Natural and recombinant mouse Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Isoform 2 self-associates; specifically in the endoplasmic reticulum prior to its translocation to the Golgi. Isoform 1 and isoform 2 interact with MGAT1, MGAT3 and MAN2A2; isoform 2 interacts specifically with MGAT1 in the Golgi.
Isoform 2: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
Isoform 1 Golgi apparatus membrane Single-pass type II membrane protein
MKAKNVNLLF | AFVAVLLFGF | SCFCISRMNQ | TNNQLINCRN | HVLEFKEIML |
RLKNKSENHH | QDLMQVLYQ | MKRKAAHTTR | SSGNFLEKKG | SILSQHETLP |
NQFEVLKYFL | PHLRTAGKLY | P AIATSKGR | AGVSFALGIS | TINRGNHTYL |
KQTLTSVLSR | MTPEEEEDSV | VIVSVADTDE | SY LKSVVRM | VKTKFRKQVQ |
SGVLEVISIP | TLFYPQTLLD | KKTKTDSESW | QIKQVLDFCI | LML YAQPKA |
TYYLQLEDDI | VAKKMYFTKM | KDFVNSLTSK | NWFFIEFSVL | GFIGKLFRSK |
DLTD FVHFF | LMFYETKPID | ILLDDIFLIR | VCISGEPVRS | CLQRKKGFRI |
QYRPSLFQHV | GTQSS FPGR | EQHLKDNYY
This product has not yet been referenced specifically in any publications.
"GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain."
"A testis-specific regulator of complex and hybrid N-glycan synthesis."
"ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis."
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
"Genome-wide association with select biomarker traits in the Framingham Heart Study."
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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