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MGME1 (基因名), Mitochondrial genome maintenance exonuclease 1 (蛋白名), MGME1_HUMAN.
产品名称:

Human MGME1/ Mitochondrial genome maintenance exonuclease 1 ELISA Kit
线粒体基因组维护外切酶1

货号:

E15155h

商标:
EIAab®
监管等级:
别名:

C20orf72, DDK1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.136ng/mL
特异性:
Natural and recombinant human Mitochondrial genome maintenance exonuclease 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human MGME1 ELISA Kit
规格 & 价格: cart
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Human MGME1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

94-103%

84-93%

109-118%

103-112%

EDTA plasma(n=5)

82-92%

110-119%

96-105%

108-118%

heparin plasma(n=5)

102-113%

 

101-111%

90-100%

98-108%

 

通用注释


亚单元:
N/A


功能:
Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.


亚细胞位置:
Mitochondrion


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