Acsf3 (GeneName), Malonate--CoA ligase ACSF3, mitochondrial (ProteinName), ACSF3_MOUSE.
Mouse Acsf3/ Malonate--CoA ligase ACSF3, mitochondrial ELISA Kit
6.2.1.n3, Acyl-CoA synthetase family member 3
Natural and recombinant mouse Malonate--CoA ligase ACSF3, mitochondrial
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates.
MPPHLALPFR | RLFWSLASSQ | LIPRRHRGHS | LLPTTPEAHT | DGSVPVFIRA |
LAFGDRIALI | DKYGHHTYR | ELYDRSLCLA | QEICRLQGCK | VGDLQEERVS |
FLCSNDVSYV | VAQWASWMSG | G VAVPLYWK | HPEAQLEYFI | QDSRSSLVVV |
GQEYLERLSP | LAQRLGVPLL | PLTPAVYHGA | TE KPTEQPV | EESGWRDRGA |
MIFYTSGTTG | RPKGALSTHR | NLAAVVTGLV | HSWAWTKNDV | ILH VLPLHH |
VHGVVNKLLC | PLWVGATCVM | LPEFSAQQVW | EKFLSSEAPQ | ITVFMAVPTV |
YSKL LDYYD | KHFTQPHVQD | FVRAVCKERI | RLMVSGSAAL | PVPLLEKWRS |
ATGHTLLERY | GMTEI GMAL | SNPLTEARVP | GSVGTPLPGV | EVRIISENPQ |
KGSPYIIHAE | GNERGTKVTP | GFEEKE GEL | LVRGPSVFRE | YWDKPEETKS |
AFTSDGWFRT | GDTAVFKDAR | YWIRGRTSVD | IIKTGGY KV | SALEIERHLL |
AHPSITDVAV | IGVPDMTWGQ | RVTAVVALQE | GHSLSHGDLK | EWARGVLA P |
YAVPSELLLV | EEIPRNQMGK | VNKKELLKQL | YPSGQRSQPG | QG
This product has not yet been referenced specifically in any publications.
"Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome."
"Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis."
"Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria."
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency."
"Architecture of the human interactome defines protein communities and disease networks."
"Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing."
"The BioPlex Network: A Systematic Exploration of the Human Interactome."
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