ACHE (基因名), Acetylcholinesterase (蛋白名), aces_human.
产品名称:
Human ACHE/ Acetylcholinesterase CLIA Kit
乙酰胆碱脂
货号:
U1195h
商标:
EIAab®
监管等级:
别名:
AChE
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Acetylcholinesterase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Interacts with PRIMA1. The interaction with PRIMA1 is required to anchor it to the basal lamina of cells and organize into tetramers (By similarity). Isoform H generates GPI-anchored dimers; disulfide linked. Isoform T generates multiple structures, ranging from monomers and dimers to collagen-tailed and hydrophobic-tailed forms, in which catalytic tetramers are associated with anchoring proteins that attach them to the basal lamina or to cell membranes. In the collagen-tailed forms, isoform T subunits are associated with a specific collagen, COLQ, which triggers the formation of isoform T tetramers, from monomers and dimers. Isoform R may be monomeric.
功能:
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
亚细胞位置:
Isoform H
Cell membrane
Lipid-anchor
GPI-anchor
Extracellular side
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