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MIF (基因名), Macrophage migration inhibitory factor (蛋白名), mif_human.

产品名称:

MIF Antibody

货号:

P0698Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase, GIF, MIF, GLIF, MMIF

序列号:

P14174

反应性:

human, rat,mouse

免疫原:

Recombinant human MIF Protein (R0698h)

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Immunology

规格 & 价格:

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Human MIF Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemical of paraffin-embedded human lung using MIF antibody at dilution of 1:50.?

通用注释

亚单元:

Homotrimer. Interacts with CXCR2 extracellular domain (By similarity). Interacts with the CD74 extracellular domain, COPS5 and BNIPL.

功能:

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

亚细胞位置:

Secreted Cytoplasm Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.

数据库链接

UniGene:

Hs.407995

SMR:

P14174

STRING:

9606.ENSP00000215754

KEGG:

hsa:4282

MIM:

153620

Pfam: