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CCN2 (基因名), CCN family member 2 (蛋白名), ccn2_human.
产品名称:

Human CCN2/ CCN family member 2 Recombinant Protein
结缔组织生长因子

货号:

R0010h

商标:
EIAab®
监管等级:
别名:

Cellular communication network factor 2, Connective tissue growth factor, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, CTGF, HCS24, IGFBP8

序列号:
P29279
来源:
E.coli
种属:
Human
标签:
His
序列:
CAYRLEDTFGPDPTMI
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human CCN2 Protein
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Human CCN2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 6q23.2 by HGNC 6q23.2 by Entrez Gene 6q23.2 by Ensembl
CCN2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer.


功能:
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.


亚细胞位置:
Secreted Extracellular space Extracellular matrix Secreted


该产品尚未在任何出版物中被引用。

[1].
"Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor."

[2].
"The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion."

[3].
"Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10."

[4].
"FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells."

[5].
"Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia."

[6].
"Impaired intracellular signaling may allow up-regulation of CTGF-synthesis and secondary peri-retinal fibrosis in human retinal pigment epithelial cells from patients with age-related macular degeneration."

[7].
"Renal proximal tubular dysfunction is a major determinant of urinary connective tissue growth factor excretion."

[8].
"Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation."

[9].
"Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate."

[10].
"Hyaluronic acid modulates gene expression of connective tissue growth factor (CTGF), transforming growth factor-beta1 (TGF-beta1), and vascular endothelial growth factor (VEGF) in human fibroblast-like synovial cells from advanced-stage osteoarthritis in vitro."
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