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EPB41 (基因名), Erythroid protein 4.1 (蛋白名), 41_CHICK.
产品名称:

Chicken EPB41/ Erythroid protein 4.1 Recombinant Protein

货号:

R11605c

商标:
EIAab®
监管等级:
别名:

Band 4.1

来源:
E.coli
种属:
Chicken
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Chicken EPB41 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


Sub Unit:
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Binds calmodulin and DLG1.


Function:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. May be required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.


Subcellular Location:
Nucleus Cytoplasm Cytoskeleton Cytoplasm Cell cortex


该产品尚未在任何出版物中被引用。

[1].
"An alternative domain containing a leucine-rich sequence regulates nuclear cytoplasmic localization of protein 4.1R."

[2].
"Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization."

[3].
"Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase."

[4].
"Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population."

[5].
"Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation."
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