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ASPRO (短名 ),
产品名称:

Human ASPRO/ Asprosin Recombinant Protein
Asprosin

货号:

R15190-1h

商标:
EIAab®
监管等级:
序列号:
P35555
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ASPRO Protein
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Human ASPRO Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
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通用注释


亚单元:
Asprosin, a fasting-induced glucogenic protein homone that modulates hepatic glucose release. It is the C-terminal cleavage product of profibrillin, and encoded by the ultimate two exons of FBN1.


功能:
Circulating asprosin, a protein hormone, responds to low dietary glucose by triggering the release of liver glucose stores, and the reduction of asprosin protects against the hyperinsulinism associated with metabolic syndrome.


Location:
Asprosin circulates at nanomolar levels, a single dose of recombinant asprosin retains biological activity and elevates blood glucose and insulin levels. Liver is the target organ for asprosin to recruit. Asprosin increases hepatocyte glucose release through activating the G protein-cAMP-PKA pathway.


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