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AANAT (基因名), Serotonin N-acetyltransferase (蛋白名), snat_human.
产品名称:

AANAT Antibody

货号:

P1937Rb

商标:
EIAab®
监管等级:
别名:

Aralkylamine N-acetyltransferase, AA-NAT, Serotonin acetylase, SNAT

序列号:
Q16613
反应性:
human,mouse,rat
免疫原:
corresponding to a sequence mapping at the 1-70aa of Q16613
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Neurosciences
  • Human AANAT Polyclonal Antibody
  • Human AANAT Polyclonal Antibody
  • Human AANAT Polyclonal Antibody
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Human AANAT Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human AANAT Polyclonal Antibody
Y79 cell proteinwas subjected to SDS-PAGE followed by Western Blot with Serotonin N-acetyltransferaseantibody at dilution of 1:300
Immunohistochemical analysis of formalin-fixed and paraffin embedded rat brain tissue (dilution at 1:250) using AANAT antibody.
通用注释


亚单元:
Monomer (By similarity). Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ, preferentially when phosphorylated at Thr-31. Phosphorylation on Ser-205 also allows binding to YWHAZ, but with lower affinity. The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protects the enzyme from dephosphorylation and proteasomal degradation (By similarity). It may also prevent thiol-dependent inactivation.


功能:
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.


亚细胞位置:
Cytoplasm


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