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ABCC1 (基因名), Multidrug resistance-associated protein 1 (蛋白名), mrp1_human.
产品名称:

ABCC1 Antibody

货号:

P1068Rb-h

商标:
EIAab®
监管等级:
别名:

ATP-binding cassette sub-family C member 1, Glutathione-S-conjugate-translocating ATPase ABCC1, Leukotriene C(4) transporter, LTC4 transporter, MRP, MRP1

序列号:
P33527
反应性:
human
免疫原:
Recombinant human ABCC1 protein ( R1068h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Signal Transduction
  • Human ABCC1 Polyclonal Antibody
  • Human ABCC1 Polyclonal Antibody
  • Human ABCC1 Polyclonal Antibody
规格 & 价格: cart
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Human ABCC1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ABCC1 Polyclonal Antibody
Ramos cell lysates was subjected to SDS-PAGE followed by Western Blot with Multidrug resistance-associated protein 1antibody at dilution of 1:300
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in a subset of cells in glomeruli.
通用注释


亚单元:
N/A


功能:
Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:9281595). Hydrolyzes ATP with low efficiency (PubMed:16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed:17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).


亚细胞位置:
Cell membrane Multi-pass membrane protein


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