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ACACA (基因名), Acetyl-CoA carboxylase 1 (蛋白名), acaca_human.
产品名称:

ACACA Antibody

货号:

P1284Rb-h

商标:
EIAab®
监管等级:
别名:

Acetyl-Coenzyme A carboxylase alpha, ACC-alpha, ACC1, ACAC, ACC1, ACCA

序列号:
Q13085
反应性:
human
免疫原:
Recombinant human ACACA protein ( R1284h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Metabolism
  • Human ACACA Polyclonal Antibody
  • Human ACACA Polyclonal Antibody
  • Human ACACA Polyclonal Antibody
规格 & 价格: cart
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Human ACACA Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
Human ACACA Polyclonal Antibody
HELA cell was subjected to SDS-PAGE followed by Western Acetyl-CoA carboxylase 1antibody at dilution of 1:300
Acetyl CoA Carboxylase 1 antibody detects Acetyl CoA Carboxylase 1 protein at cytoplasm in mouse cervix by immunohistochemical analysis.Acetyl CoA Carboxylase 1 antibody diluted at 1:500.
通用注释


亚单元:
Monomer, homodimer, and homotetramer (PubMed:20952656). Can form filamentous polymers (PubMed:20457939, PubMed:20952656). Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis (PubMed:12360400, PubMed:16326698). Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity (PubMed:20457939).


功能:
Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA, a key metabolite in the fatty acid synthetic (PubMed:20952656, PubMed:20457939). Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (PubMed:20952656, PubMed:20457939).


亚细胞位置:
Cytoplasm


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