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A2M (基因名), Alpha-2-macroglobulin (蛋白名), a2mg_human.
产品名称:

A2M Antibody

货号:

P1017Rb-h

商标:
EIAab®
监管等级:
别名:

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, FWP007, Alpha-2-M, CPAMD5

序列号:
P01023
反应性:
human
免疫原:
Recombinant human A2M protein ( R1017h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
  • Human A2M Polyclonal Antibody
  • Human A2M Polyclonal Antibody
  • Human A2M Polyclonal Antibody
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Human A2M Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human A2M Polyclonal Antibody
HepG2 cells proteinwas subjected to SDS-PAGE followed by Western Blot with Alpha-2-macroglobulin antibody at dilution of 1:300
Immunohistochemical staining of human liver using A2M antibody shows moderate cytoplasmic positivity in hepatocytes.
通用注释


亚单元:
Homotetramer; disulfide-linked.


功能:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.


亚细胞位置:
Secreted


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