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Adra1a (基因名), Alpha-1A adrenergic receptor (蛋白名), ada1a_mouse.
产品名称:

Mouse Adra1a/ Alpha-1A adrenergic receptor ELISA Kit
Alpha-1A肾上腺素能受体

货号:

E1298m

商标:
EIAab®
监管等级:
别名:

Alpha-1A adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-1A adrenoceptor, Adra1c

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.086ng/mL
特异性:
Natural and recombinant mouse Alpha-1A adrenergic receptor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Mouse Adra1a ELISA Kit
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤7.0%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤9.2%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

106

100-112

Plasma

108

102-114

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

98-107%

100-110%

103-115%

91-101%

EDTA plasma(n=5)

107-116%

117-117%

92-101%

106-117%

heparin plasma(n=5)

106-116%

 

106-118%

101-110%

106-118%

 

通用注释


亚单元:
Homo- and heterooligomer. Heterooligomerizes with ADRA1B homooligomers in cardiac myocytes.


功能:
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.


亚细胞位置:
Nucleus membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes (By similarity).


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