EIAab
首页  >  酶联免疫试剂盒  >  Human SORBS1 ELISA Kit
SORBS1 (基因名), Sorbin and SH3 domain-containing protein 1 (蛋白名), SRBS1_HUMAN.
产品名称:

Human SORBS1/ Sorbin and SH3 domain-containing protein 1 ELISA Kit
含有Sorbin和SH3结构域的蛋白1

货号:

E3361h

商标:
EIAab®
监管等级:
别名:

Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP, KIAA0894, KIAA1296, SH3D5

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/ml
灵敏度:
0.12ng/mL
特异性:
Natural and recombinant human Sorbin and SH3 domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human SORBS1 ELISA Kit
规格 & 价格: cart
×
Human SORBS1 ELISA Kit
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤4.2%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤8.3%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

99

93-105

Plasma

101

95-107

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

102-111%

104-113%

85-97%

100-108%

EDTA plasma(n=5)

110-120%

106-117%

102-111%

110-119%

heparin plasma(n=5)

87-98%

 

100-109%

100-109%

109-119%

 

通用注释


亚单元:
Interacts (via third SH3 domain) with the Ten-1 ICD form of TENM1; the interaction induces the translocation of SORBS1 to the nucleus. Interacts with INSM1 (By similarity). Interacts with the long isoform of AFDN and with VCL. AFDN and VCL bind to SORBS1 in a competitive manner and do not form a ternary complex. Interacts with ABL1, CBL, CBLB and INPPL1/SHIP2 through the third SH3 domain. Interaction with ABL1 occurs only after insulin stimulation while this has no effect on the interaction with INPPL1. Interacts with the insulin receptor but dissociates from it following insulin stimulation. Also interacts with SCA7, PTK2/FAK1 and flotillin. Interacts (via SH3 domain 2) with PXN.


功能:
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.


亚细胞位置:
Cell junction Adherens junction Cell membrane Cytoplasm Cytoskeleton Cell junction Focal adhesion Nucleus Nucleus matrix Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.


该产品尚未在任何出版物中被引用。
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com