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PEG10 (基因名), Retrotransposon-derived protein PEG10 (蛋白名), PEG10_HUMAN.
产品名称:

Human PEG10/ Retrotransposon-derived protein PEG10 ELISA Kit
逆转录转座子衍生蛋白PEG10

货号:

E3142h

商标:
EIAab®
监管等级:
别名:

Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, MEF3-like protein 1, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/ml
灵敏度:
0.19ng/mL
特异性:
Natural and recombinant human Retrotransposon-derived protein PEG10
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Human PEG10 ELISA Kit
规格 & 价格: cart
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Human PEG10 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤5.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤9.2%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

101

95-107

Plasma

103

97-109

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

103-114%

100-110%

87-98%

91-100%

EDTA plasma(n=5)

108-118%

92-103%

99-110%

104-114%

heparin plasma(n=5)

90-99%

 

108-108%

106-116%

105-115%

 

通用注释


亚单元:
Interacts with ALK1, SIAH1 and SIAH2.


功能:
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter.


亚细胞位置:
Nucleus Cytoplasm Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the Hep-G2 cell line. Colocalized with ALK1.


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