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ADIPOR1 (基因名), Adiponectin receptor protein 1 (蛋白名), PAQR1_HUMAN.
产品名称:

Human ADIPOR1/ Adiponectin receptor protein 1 ELISA Kit
脂联素受体蛋白1

货号:

E2221h

商标:
EIAab®
监管等级:
别名:

Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I, CGI-45, PAQR1, TESBP1A

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/ml
灵敏度:
0.32ng/mL
特异性:
Natural and recombinant human Adiponectin receptor protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Immunology
Human ADIPOR1 ELISA Kit
规格 & 价格: cart
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Human ADIPOR1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤5.5%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤6.9%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

100

94-106

Plasma

102

96-108

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

101-110%

89-101%

102-111%

97-107%

EDTA plasma(n=5)

105-105%

92-102%

89-101%

96-105%

heparin plasma(n=5)

107-116%

 

118-118%

95-104%

104-114%

 

通用注释


亚单元:
May form homooligomers and heterooligomers with ADIPOR2 (PubMed:12802337). Interacts with APPL2 (via BAR domain); hinders the accessibility of APPL1 to ADIPOR1; negatively regulates adiponectin signaling; ADIPOQ dissociates this interaction and facilitates the recruitment of APPL1 to ADIPOR1. Interacts with APPL1; ADIPOQ enhances this interaction; inhibites adiponectin-stimulated binding of APPL2 to ADIPOR1 (By similarity).


功能:
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).


亚细胞位置:
Cell membrane Multi-pass membrane protein Localized to the cell membrane and intracellular organelles.


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