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MRC2 (基因名), C-type mannose receptor 2 (蛋白名), MRC2_HUMAN.
产品名称:

Human MRC2/ C-type mannose receptor 2 ELISA Kit
C-型甘露糖受体2

货号:

E2105h

商标:
EIAab®
监管等级:
别名:

C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein, UPAR-associated protein, CD280, CLEC13E, ENDO180, KIAA0709, UPARAP

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.15ng/mL
特异性:
Natural and recombinant human C-type mannose receptor 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Immunology
Human MRC2 ELISA Kit
规格 & 价格: cart
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Human MRC2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤4.8%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤7.8%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

107

101-113

Plasma

109

103-115

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

106-117%

102-111%

94-104%

95-104%

EDTA plasma(n=5)

104-113%

107-116%

105-115%

96-106%

heparin plasma(n=5)

110-120%

 

89-98%

89-98%

102-112%

 

通用注释


亚单元:
Interacts with C-terminal region of type I collagen/COL1A1 (By similarity). Interacts directly with PLAUR/UPAR and PLAU/pro-UPA to form a tri-molecular complex. Interacts with collagen V.


功能:
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).


亚细胞位置:
Membrane Single-pass type I membrane protein


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