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Mpeg1 (基因名), Macrophage-expressed gene 1 protein (蛋白名), MPEG1_MOUSE.
产品名称:

Mouse Mpeg1/ Macrophage-expressed gene 1 protein ELISA Kit
HumanMPEG1

货号:

E15112m

商标:
EIAab®
监管等级:
别名:

Perforin-2, Protein MPS1, P-2, Macrophage gene 1 protein

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant mouse Macrophage-expressed gene 1 protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Mpeg1 ELISA Kit
规格 & 价格: cart
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Mouse Mpeg1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: 0
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 0
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

80

80-80

Plasma

80

80-80

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

96-106%

106-119%

110-122%

84-96%

EDTA plasma(n=5)

101-110%

101-111%

106-118%

100-109%

heparin plasma(n=5)

107-119%

 

99-108%

85-95%

101-111%

 

通用注释


亚单元:
N/A


功能:
Plays a key role in the innate immune response following bacterial infection by polymerizing and inserting into the bacterial surface to form pores (PubMed:26402460). By breaching the surface of phagocytosed bacteria, allows antimicrobial effectors to enter the bacterial periplasmic space and degrade bacterial proteins such as superoxide dismutase sodC which contributes to bacterial virulence (PubMed:30249808). Shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria (PubMed:23257510, PubMed:23753625, PubMed:26402460). Reduces the viability of the intracytosolic pathogen L.monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol (PubMed:26831467). Required for the antibacterial activity of reactive oxygen species and nitric oxide (PubMed:26402460).


亚细胞位置:
Cytoplasmic vesicle membrane Single-pass type I membrane protein Bacterial infection induces translocation of the cytoplasmic vesicles to bacterium-containing phagocytic vesicles and fusing of the vesicles.


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