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MCM7 (基因名), DNA replication licensing factor MCM7 (蛋白名), MCM7_HUMAN.
产品名称:

Human MCM7/ DNA replication licensing factor MCM7 ELISA Kit

货号:

E11173h

商标:
EIAab®
监管等级:
别名:

CDC47 homolog, P1.1-MCM3, CDC47, MCM2

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
1.56-100ng/mL
灵敏度:
0.69ng/mL
特异性:
Natural and recombinant human DNA replication licensing factor MCM7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human MCM7 ELISA Kit
规格 & 价格: cart
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Human MCM7 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Component of the MCM2-7 complex. The complex forms a toroidal hexameric ring with the proposed subunit order MCM2-MCM6-MCM4-MCM7-MCM3-MCM5 (Probable). Interacts with the ATR-ATRIP complex and with RAD17. Interacts with TIPIN. Interacts with MCMBP. Interacts with ANKRD17.


功能:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.


亚细胞位置:
Nucleus


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