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MTDH (基因名), Protein LYRIC (蛋白名), LYRIC_HUMAN.
产品名称:

Human MTDH/ Protein LYRIC ELISA Kit
蛋白质抒情

货号:

E1442h

商标:
EIAab®
监管等级:
别名:

3D3/LYRIC, Astrocyte elevated gene-1 protein, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein, AEG-1, AEG1, LYRIC

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
1.56-100nmol/L
灵敏度:
0.092nmol/L
特异性:
Natural and recombinant human Protein LYRIC
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Human MTDH ELISA Kit
规格 & 价格: cart
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Human MTDH ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤3.2%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤6.5%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

104

98-110

Plasma

106

100-112

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

102-111%

80-90%

88-98%

96-108%

EDTA plasma(n=5)

105-115%

89-99%

107-117%

96-107%

heparin plasma(n=5)

89-99%

 

116-128%

91-99%

101-109%

 

通用注释


亚单元:
Interacts with BCCIP, CREBBP/CBP and RELA/p65.


功能:
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein Nucleus membrane Single-pass membrane protein Cell junction Tight junction Nucleus Nucleolus Cytoplasm Perinuclear region In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain (By similarity). TNF-alpha causes translocation from the cytoplasm to the nucleus.


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