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ITLN1 (基因名), Intelectin-1 (蛋白名), ITLN1_HUMAN.
产品名称:

Human ITLN1/ Intelectin-1 ELISA Kit
内凝集蛋白-1

货号:

E0933h

商标:
EIAab®
监管等级:
别名:

Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, UNQ640/PRO1270, ITLN-1, INTL, ITLN, LFR

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/mL
灵敏度:
0.32ng/mL
特异性:
Natural and recombinant human Intelectin-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Human ITLN1 ELISA Kit
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Human ITLN1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤5.2%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤8.8%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

101

95-107

Plasma

103

97-109

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

101-110%

108-116%

98-108%

110-120%

EDTA plasma(n=5)

92-102%

104-113%

92-101%

87-97%

heparin plasma(n=5)

88-101%

 

81-89%

99-110%

106-116%

 

通用注释


亚单元:
Homotrimer; disulfide-linked (PubMed:11313366, PubMed:17621593, PubMed:26148048). May interact with LTF (PubMed:11747454, PubMed:23921499).


功能:
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:11313366, PubMed:26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed:26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed:26148048). Does not bind human glycans (PubMed:26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed:16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed:16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed:11747454, PubMed:23921499).


亚细胞位置:
Cell membrane Lipid-anchor GPI-anchor Secreted Enriched in lipid rafts.


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