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Ifitm3 (基因名), Interferon-induced transmembrane protein 3 (蛋白名), IFM3_MOUSE.
产品名称:

Mouse Ifitm3/ Interferon-induced transmembrane protein 3 ELISA Kit
干扰素有道跨膜蛋白3

货号:

E10026m

商标:
EIAab®
监管等级:
别名:

Dispanin subfamily A member 2b, Fragilis protein, Interferon-inducible protein 15, Mouse ifitm-like protein 1, DSPA2b, Mil-1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.078-5ng/mL
灵敏度:
0.037ng/mL
特异性:
Natural and recombinant mouse Interferon-induced transmembrane protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Ifitm3 ELISA Kit
规格 & 价格: cart
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Mouse Ifitm3 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

103-115%

85-94%

101-110%

107-117%

EDTA plasma(n=5)

99-109%

100-110%

100-111%

95-107%

heparin plasma(n=5)

94-104%

 

83-94%

85-93%

102-112%

 

通用注释


亚单元:
Interacts with SPP1; the interaction reduces OPN expression (By similarity). Interacts with ATP6V0B and CD81.


功能:
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV) and human immunodeficiency virus type 1 (HIV-1). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state. Involved in initiating germ cell competence and specification, and in the demarcation of PGCs from their somatic neighbors.


亚细胞位置:
Cell membrane Single-pass type II membrane protein Late endosome membrane Single-pass type II membrane protein Lysosome membrane Single-pass type II membrane protein


该产品尚未在任何出版物中被引用。
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