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MR1 (基因名), Major histocompatibility complex class I-related gene protein (蛋白名), HMR1_HUMAN.
产品名称:

Human MR1/ Major histocompatibility complex class I-related gene protein ELISA Kit
主要组织相容性复合体i类相关基因蛋白

货号:

E0910h

商标:
EIAab®
监管等级:
别名:

Class I histocompatibility antigen-like protein, MHC class I-related gene protein

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.05ng/mL
特异性:
Natural and recombinant human Major histocompatibility complex class I-related gene protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human MR1 ELISA Kit
规格 & 价格: cart
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Human MR1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤4.2%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤7.8%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

101

95-107

Plasma

103

97-109

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

110-120%

86-96%

92-101%

86-86%

EDTA plasma(n=5)

93-105%

103-115%

109-119%

111-119%

heparin plasma(n=5)

102-111%

 

110-119%

116-116%

91-101%

 

通用注释


亚单元:
Heterodimerizes with B2M, this interaction is required for surface expression. Associated with the peptide-loading complex, TAPBP, CALR and PDIA3. Isoform 3/MR1B homodimerizes and doesn't associates with B2M nor proteins of the peptide-loading complex.


功能:
Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.


亚细胞位置:
Isoform 3 Cell membrane Single-pass type I membrane protein Endoplasmic reticulum membrane The larger proportion remains in the ER in an immature state. The subset that reach cell surface does it through a B2M-independent pathway.


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